ICPE
	The Interdisciplinary Center Psychopathology and Emotion regulation (ICPE) Hanzeplein 1 – Entrance 24 (Triadegebouw) Groningen PO box 30.001, Hospital mail address CC72 9700 RB Groningen Tel: 050-361 1242/1712 Fax: 050-361 9722 e-mail: icpe@med.umcg.nl Aim The Interdisciplinary Center Psychopathology and Emotion regulation (ICPE) aims to perform high-quality psychiatric research at the crossroads of various disciplines, including Psychiatry, Epidemiology, Social Sciences, Neurosciences, and Internal Medicine. The program focuses on common mental health problems, with a special emphasis on affective disorders. Main goals are to unravel psychobiological processes involved in the onset and course of affective disorders, and to develop and evaluate personalized interventions to improve mood-related problems and social-emotional functioning. Affective problems account for a large proportion of the burden of disease throughout the life span. Apart from being a cause of suffering on their own, they are also highly prevalent in somatic and psychotic disorders, and interfere with their course. Affective problems are often rooted in early life, with diverging expressions and consequences in subsequent phases of life. These characteristics render affective disorders particularly relevant for healthy ageing. Approach The interdisciplinary nature of the ICPE is reflected in both the research themes and the methods used. Large longitudinal epidemiological surveys (e.g., TRAILS, NESDA, LifeLines) are complemented with studies involving more, or more in-depth, measurements in smaller groups to elucidate underlying endophenotypes and temporal patterns. The study designs are both observational and experimental, and involve a variety of (neuro)psychological, social, and biological measures, including neuroimaging techniques. Specific research themes include questions regarding trajectories of mental health, person-environment transactions and interactions, emotion regulation in psychotic disorders, and psychopathology in the context of somatic conditions. The ultimate goal is to identify high-risk groups and causal risk or protective factors in order to develop more effective, personalized prevention and intervention strategies for mood and mood-related problems and social-emotional functioning. Principal investigators ICPE Prof. dr. P. de Jonge (program leader) Prof. dr. A.J. Oldehinkel (program leader) Dr. H. Burger Dr. C.A. Hartman Prof. dr. W.A. Nolen Prof. dr. J. Ormel Prof. dr. R.C. Oude Voshaar Dr. H. Riese Prof. dr. J.G.M. Rosmalen Prof. dr. R.A. Schoevers Dr. S. Sytema ICPE-NIC Prof. dr. A. Aleman Dr. S. Martens Dr. R. Kortekaas